DL-Methionine 99.0-101.0% Ph. Eur., NF

Synonyms: Methionine racematic(±)-2-Amino-4-(methylthio)butyric acid(±)-2-Amino-4-(methylthio)butanoic acid(±)-Methionine2-Amino-4-(methylthio)butanoic acidH-DL-Met-OHMethioninum racemicum

16236.366EA 81834 INR
16236.366 16236.297
DL-Methionine 99.0-101.0% Ph. Eur., NF
DL-Methionine

Appearance: Almost white, crystalline powder or small flakes.


Caution: Not for use as Active Pharmaceutical Ingredient (API)

Formula: C₅H₁₁NO₂S
MW: 149,21 g/mol
Melting Pt: ∼136 °C
Density: 1,34 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00063096
CAS Number: 59-51-8
EINECS: 200-432-1
Merck Index: 13,06004

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Specification Test Results

Appearance Conforms (see CoA/CoS)
Heavy metals (as Pb) Max. 5 ppm
Residual solvents (Ph.Eur./ICH) Unlikely by manuf.process
Residues of metal catalysts or reagents Unlikely by manuf.process
As (Arsenic) Max. 2 ppm
Cd (Cadmium) Max. 1 ppm
Co (Cobalt) Max. 1 ppm
Hg (Mercury) Max. 3 ppm
Ni (Nickel) Max. 1 ppm
Pb (Lead) Max. 2 ppm
V (Vanadium) Max. 2 ppm
Conforms to Ph.Eur./NF Passes test
Ph.Eur. specifications:
Assay (calculated on dried) [Ph.Eur.] 99.0 --> 101.0 %
Identification A Passes test Ph.Eur.
Identification C [Ph.Eur.] -0.05 --> 0.05 °
Appearance of solution Passes test Ph.Eur.
pH (2 %) [Ph.Eur.] 5.4 --> 6.1
Related substances [Ph.Eur.] Max. 0.2 %
Cl (Chloride) [Ph.Eur.] Max. 200 ppm
SO4 (Sulphate) [Ph.Eur.] Max. 200 ppm
Loss on drying (105°C) [Ph.Eur.] Max. 0.5 %
Sulphated ash [Ph.Eur.] Max. 0.1 %
NF specifications:
Assay (calculated on dried basis) [NF] 99.0 --> 101.0 %
Identification A Passes test NF
Identification B Passes test NF
Identification C [NF] -0.05 --> 0.05 °
Identification D Passes test NF
Residue on ignition [NF] Max. 0.1 %
Cl (Chloride) [NF] Max. 200 ppm
SO4 (Sulphate) [NF] Max. 200 ppm
Limit of iron [NF] Max. 10 ppm
Limit of ammonium [NF] Max. 200 ppm
Related substances [NF] Max. 0.2 %
pH (25°C; 20 mg/ml) [NF] 5.4 --> 6.1
Loss on drying (105°C; 3 h) [NF] Max. 0.5 %
T (430 nm) (10 %; HCl 2 N) [NF] Min. 98 %

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