TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride) ≥99.0% for biopharmaceutical production

Supplier: VWR Chemicals

Synonyms: Tris(hydroxymethyl)aminomethane hydrochlorideTris(hydroxymethyl)methylamine hydrochlorideTrizma(R) hydrochlorideTris(hydroxymethyl)methylammonium chlorideTHAM HClTrometamol hydrochloride2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochlorideTRIS HCl

85827.297EA 12047 INR
85827.297 85827.366 85827.468
TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride) ≥99.0% for biopharmaceutical production
TRIS HCl (Tris-(hydroxymethyl) aminomethane hydrochloride)
Formula: NH₂C(CH₂OH)₃·HCl
MW: 157,6 g/mol
Melting Pt: 150…152 °C
Storage Temperature: Ambient
MDL Number: MFCD00012590
CAS Number: 1185-53-1
EINECS: 214-684-5
Merck Index: 12,09902
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Specification Test Results

Assay Min. 99,0 %
Appearance White crystalline powder
Cell culture toxicity Passes test
Dnases Not detected
Identification by IR Conforms to structure
Proteases Not detected
Rnases Not detected
Solubility (1 mol/l) Clear and complete
pH (0,5 mol/l) 3,5 -- 5,0
pKa (25°C) 8,0 -- 8,4
Ignition residue Max. 0,1 %
Insoluble substances Max. 50 ppm
Loss on drying (105°C) Max. 0,5 %
Ca (Calcium) Max. 5 ppm
Cu (Copper) Max. 5 ppm
Fe (Iron) Max. 5 ppm
Mg (Magnesium) Max. 5 ppm
Mn (Manganese) Max. 5 ppm
Pb (Lead) Max. 5 ppm
Zn (Zinc) Max. 5 ppm
Absorbance (260 nm) (1 mol/l) Max. 0,05
Absorbance (280 nm) (1 mol/l) Max. 0,05
Bioburden Max. 100 CFU/g
Endotoxin (1 %) (EU/mg) Max. 0,1

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